Pediatric Fluid Therapy

[Perioperative fluid therapy in the pediatric patient. Recommendations].

Caloric and water requirements for basal metabolism in the hospitalized, not anesthetized children were calculated by Holliday and Segar in 1957 [1]. They developed an empirical equation estimating maintenance requirements: 100 mL/kg/day for the first 10 kg, 50 mL/kg /day for the second 10 kg and 20 ml/kg/day for the remaining kg with hypotonic solutions (saline 0.2%) containing 2-3 mEq/100 kca...

Current Thinking In Pediatric Peri-operative Fluid Therapy

Proper perioperative fluid management is critical to maintain cardiovascular stability and adequate tissue perfusion. The volume and composition of fluid should be adapting to the physiology of the child and compensating for the peri-operative events. Traditionally physicians were calculating pediatric maintenance fluid requirements based on studies conducted on healthy children more than 50 ye...

Stem Cell Therapy in Pediatric Neurological Disorders

Pediatric neurological disorders including muscular dystrophy, cerebral palsy, and spinal cord injury are defined as a heterogenous group of diseases, of which some are known to be genetic. The two significant features represented for stem cells, leading to distinguish them from other cell types are addressed as below: they can renew themselves besides the ability to differentiate into cells wi...

A review of past and current thinking in pediatric fluid therapy.

Discovering knowledge on pediatric fluid therapy and dysnatremias from quantitative data found in electronic medical records.

It is accepted that intravenous fluid (IVF) therapy can result in hospital-acquired dysnatremias in pediatric patients, with associated morbidity and mortality. There is interest in improving IVF therapy to prevent dysnatremias, but the optimal approach is controversial. In this study, we develop Natremia Deviation and Intravenous Renderer (NaDIR), a tool that preprocesses large volumes of elec...